GSK621 is a specific AMPK activator, with IC50 values of 13-30 µM for AML cells. GSK621 induces autophagy and apoptosis. GSK621 induces eiF2alpha phosphorylation-a hallmark of UPR activation[1].
Molecular Weight:
489.91
Purity:
98.03
CAS Number:
[1346607-05-3]
Formula:
C26H20ClN3O5
Target:
AMPK,Apoptosis,Autophagy
Application Notes:
MCE Product type: Reference compound1
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