BMY 7378 is a selective antagonist of alpha1D-adrenoceptor (alpha1D-AR). BMY 7378 binds to membranes expressing the cloned rat alpha1D-AR with a >100-fold higher affinity (Ki=2 nM) than binding to either the cloned rat alpha1A-AR (Ki=800 nM) or the hamster alpha1B-AR (Ki=600 nM). BMY 7378 is a 5-HT1A receptor partial agonist[1][2].
Molecular Weight:
458.42
Purity:
99.92
CAS Number:
[21102-95-4]
Formula:
C22H33Cl2N3O3
Target:
5-HT Receptor,Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound1
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