Cl-amidine (TFA), CAS [[1043444-18-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-100574B
Supplier Catalog Number:
HY-100574B
Alternative Catalog Number:
MCE-HY-100574B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Cl-amidine TFA is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 µM, 6.2 µM and 5.9 µM for PAD1, PAD3, and PAD4, respectively. Cl-amidine TFA induces apoptosis in cancer cells. Cl-amidine TFA induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine TFA prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].
Molecular Weight:
424.80
CAS Number:
[1043444-18-3]
Formula:
C16H20ClF3N4O4
Target:
Apoptosis,MicroRNA,Protein Arginine Deiminase
Application Notes:
MCE Product type: Reference compound1
* VAT and and shipping costs not included. Errors and price changes excepted
