PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In cancer cells carrying the Y220C mutant, PK7242 binds to the p53-Y220C core domain and induces growth inhibition, cell-cycle arrest, and apoptosis.
Molecular Weight:
298.36
CAS Number:
[1446352-68-6]
Formula:
C17H19FN4
Target:
MDM-2/p53
Application Notes:
Reference compound
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