Gefitinib impurity 2 is the impurity of Gefitinib. Gefitinib (ZD1839, HY-50895) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
Molecular Weight:
309.37
Purity:
99.56
CAS Number:
[246512-44-7]
Formula:
C15H23N3O4
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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