YUKA1 is a potent and cell permeable Lysine demethylase 5A (KDM5A) inhibitor, with an IC50 of 2.66 µM. YUKA1 has less inhibitory active on KDM5C (IC50 = 7.12 µM) and is inactive on KDM5B, KDM6A or KDM6B. YUKA1 can increase H3K4me3 levels and inhibit cell proliferation. YUKA1 can be used for the research of cancer, such as lung and breast cancers[1].
Molecular Weight:
292.36
Purity:
99.15
CAS Number:
[708991-09-7]
Formula:
C13H16N4O2S
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound
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