D-AP4 (D-APB, D-2-Amino-4-phosphonobutyric acid), a phosphono analogue of glutamate, is an NMDA broad spectrum excitatory amino acid receptor antagonist. D-AP4 also is an agonist for a quisqualate-sensitized AP6 site in hippocampus. D-AP4 inhibits AMPA receptor-stimulated 57Co2+ influx in cultured cerebellar granule cells (IC50 100 µM)[1][2][3].
Molecular Weight:
183.10
CAS Number:
[78739-01-2]
Formula:
C4H10NO5P
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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