2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 µM. 2-PMPA shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA is applicable to the research of neurological diseases[1][2].
Molecular Weight:
226.12
Purity:
98
CAS Number:
[173039-10-6]
Formula:
C6H11O7P
Target:
Carboxypeptidase
Application Notes:
MCE Product type: Reference compound
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