CHS-828 (GMX1778) is a competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), with an IC50 less than 25 nM. CHS-828 (GMX1778) exerts a cytotoxic effect by decreasing the cellular level of NAD+ and exhibits a potent anticancer activity[1].
Molecular Weight:
371.86
Purity:
99.28
CAS Number:
[200484-11-3]
Formula:
C19H22ClN5O
Target:
Apoptosis,NAMPT
Application Notes:
MCE Product type: Reference compound
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