SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 µM[1][2]. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR)[3].
Molecular Weight:
504.53
Purity:
99.84
CAS Number:
[126411-39-0]
Formula:
C24H42O7P2
Target:
Autophagy,HMG-CoA Reductase (HMGCR),Pregnane X Receptor (PXR)
Application Notes:
MCE Product type: Reference compound
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