GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research[1][2].
Molecular Weight:
534.05
Purity:
99.38
CAS Number:
[148642-42-6]
Formula:
C29H32ClN5O3
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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