Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis[1][2][3][4][5][6][7][8].
Molecular Weight:
167.12
Purity:
99.88
CAS Number:
[89-00-9]
Formula:
C7H5NO4
Target:
Apoptosis,Endogenous Metabolite,iGluR,NO Synthase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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