NCB-0970 is the negative control of NCB-0846 (HY-100830). NCB-0846 is an orally active, selective inhibitor for Wnt, that inhibits Traf2- and Nck-interacting kinase (TNIK) with an IC50 of 21 nM. NCB-0846 blocks TGF-beta signaling pathway by inhibiting SMAD2/3 phosphorylation and nuclear translocation[1][2].
Molecular Weight:
375.42
Purity:
98.81
CAS Number:
[2749881-54-5]
Formula:
C21H21N5O2
Target:
MAP4K,TGF-beta/Smad,Wnt
Application Notes:
MCE Product type: Reference compound
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