5,7-Dichlorokynurenic acid (sodium), CAS [[1184986-70-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-100834A
Supplier Catalog Number:
HY-100834A
Alternative Catalog Number:
MCE-HY-100834A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
5,7-DCKA (sodium)
5,7-Dichlorokynurenic acid (5,7-DCKA) sodium is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid sodium reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid sodium increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid sodium exhibits anxiolytic-like activity in rodent models and supports exploration of glycines role in NMDA receptor-mediated synaptic transmission[1][2].
Molecular Weight:
280.04
CAS Number:
[1184986-70-6]
Formula:
C10H4Cl2NNaO3
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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