IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells[1].
Molecular Weight:
432.48
Purity:
99.81
CAS Number:
[2074607-48-8]
Formula:
C26H20N6O
Target:
Porcupine,Wnt
Application Notes:
MCE Product type: Reference compound
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