ML364 is a selective ubiquitin specific peptidase 2 (USP2) inhibitor (IC50=1.1 µM) with anti-proliferative activity, which direct binds to USP2 (Kd=5.2 µM), induces an increase in cellular cyclin D1 degradation and causes cell cycle arrest. ML364 increases the levels of mitochondrial ROS and decreases in the intracellular content of ATP[1][2].
Molecular Weight:
517.54
Purity:
99.96
CAS Number:
[1991986-30-1]
Formula:
C24H18F3N3O3S2
Target:
Deubiquitinase
Application Notes:
MCE Product type: Reference compound
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