VH-298 is a highly potent inhibitor of the VHL:HIF-alpha interaction with a Kd value of 80 to 90 nM. VH-298 leads to HIF-alpha accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs[1].
Molecular Weight:
523.65
Purity:
99.83
CAS Number:
[2097381-85-4]
Formula:
C27H33N5O4S
Target:
HIF/HIF Prolyl-Hydroxylase,Ligands for E3 Ligase
Application Notes:
MCE Product type: Reference compound
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