3-MPPI (compound RN5) is a GPCR ligand with high selectivity for alpha1-adrenergic receptor, with a Ki value of 0.21 nM for alpha1-adrenergic receptor and 50 nM for 5-HT1A receptor. 3-MPPI modulates the alpha1-adrenergic receptor signaling cascade. 3-MPPI is applicable to research related to hypertension, stress-induced anxiety-like behavioral responses, and levodopa-induced dyskinesia[1].
Molecular Weight:
419.49
CAS Number:
[133399-65-2]
Formula:
C23H25N5O3
Target:
Adrenergic Receptor,G protein-coupled Bile Acid Receptor 1
Application Notes:
MCE Product type: Reference compound
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