GRL-8234 is a potent beta-secretase (BACE1) inhibitor with blood-brain barrier penetration (Ki = 1.8 nM). GRL-8234 can rescue age-related cognitive decline in Tg2576 mice. GRL-8234 can be used in the research related to Alzheimers disease (AD)[1].
Molecular Weight:
658.81
CAS Number:
[913071-81-5]
Formula:
C36H42N4O6S
Target:
Beta-secretase
Application Notes:
MCE Product type: Reference compound
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