PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 µM. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca2+ exchanger in guinea pig airway smooth muscle[1][2].
Molecular Weight:
599.30
Purity:
99.9
CAS Number:
[192575-19-2]
Formula:
C14H10N3Na4O12PS2
Target:
Na+/Ca2+ Exchanger,P2X Receptor
Application Notes:
MCE Product type: Reference compound1
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