LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 µM for PI3Kalpha, PI3Kdelta and PI3Kbeta, respectively[1]. LY294002 also inhibits CK2 with an IC50 of 98 nM[2]. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 µM. LY294002 is an apoptosis activator[3].
Molecular Weight:
307.34
Purity:
99.95
CAS Number:
[154447-36-6]
Formula:
C19H17NO3
Target:
Apoptosis,Autophagy,Casein Kinase,DNA-PK,PI3K
Application Notes:
MCE Product type: Reference compound
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