NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM, Kds of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins[1].
Molecular Weight:
353.40
Purity:
99.53
CAS Number:
[1884640-99-6]
Formula:
C18H15N3O3S
Target:
Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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