PI-103 Hydrochloride is a dual PI3K and mTOR inhibitor with IC50s of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, and 83 nM for p110alpha, p110beta, p110delta, p110gamma, mTORC1, and mTORC2. PI-103 Hydrochloride also inhibits DNA-PK with an IC50 of 2 nM. PI-103 Hydrochloride induces autophagy[1][2][3][4].
Molecular Weight:
384.82
Purity:
98.55
CAS Number:
[371935-79-4]
Formula:
C19H17ClN4O3
Target:
Apoptosis,Autophagy,DNA-PK,mTOR,PI3K
Application Notes:
MCE Product type: Reference compound1
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