THK-5117, an arylquinoline derivative, displays high binding affinity to tau fibrils with a Ki of 10.5 nM. THK-5117 has high binding affinity to tau protein aggregates and tau-rich Alzheimer disease (AD) brain homogenates. 18F-THK-5117 has the potential to act as a tau imaging PET probe[1].
Molecular Weight:
326.36
Purity:
98.52
CAS Number:
[1374107-54-6]
Formula:
C19H19FN2O2
Target:
Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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