SB-203186 hydrochloride is a potent, selective and competitive 5-HT4 antagonist. SB-203186 hydrochloride antagonizes the 5-HT4 receptor-mediated relaxations of the carbachol-contracted rat isolated oesophagus against 5-HT with pKB values of 10.9 (rat oesophagus), 9.5 (guinea-pig ileum), and 9.0 (human colon) respectively[1][2][3].
Molecular Weight:
308.80
Purity:
99.94
CAS Number:
[207572-69-8]
Formula:
C16H21ClN2O2
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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