L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action[1][2].
Molecular Weight:
472.38
Purity:
99.9
CAS Number:
[148451-96-1]
Formula:
C22H18F6N2O3
Target:
Neurokinin Receptor
Application Notes:
MCE Product type: Reference compound1
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