Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel1b) over MT1 (Mel1a) with Ki values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity[1][2][3].
Molecular Weight:
292.37
Purity:
99.62
CAS Number:
[117946-91-5]
Formula:
C19H20N2O
Target:
Melatonin Receptor
Application Notes:
MCE Product type: Reference compound1
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