HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1].
Molecular Weight:
469.53
Purity:
99.16
CAS Number:
[1435265-06-7]
Formula:
C28H27N3O4
Target:
Formyl Peptide Receptor (FPR)
Application Notes:
MCE Product type: Reference compound
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