UPF-523 (AIDA), a rigid (carboxyphenyl) glycine derivative, is a relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a) with an IC50 of 214 µM. But UPF-523 has no effect on group II (mGlu2), group III (mGlu4) receptors or ionotropic glutamate receptors. UPF-523 has the potential for the research of the acute arthritis[1][2].
Molecular Weight:
221.21
Purity:
99.89
CAS Number:
[168560-79-0]
Formula:
C11H11NO4
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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