DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 µM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 µM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 µM). DCG-IV has anticonvulsive and neuroprotective effects[1][2].
Molecular Weight:
203.15
Purity:
99
CAS Number:
[147782-19-2]
Formula:
C7H9NO6
Target:
mGluR
Application Notes:
MCE Product type: Reference compound
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