(+)-Niguldipine (hydrochloride), CAS [[113145-69-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-101390
Supplier Catalog Number:
HY-101390
Alternative Catalog Number:
MCE-HY-101390-5MG,MCE-HY-101390-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
(S)-Niguldipine (hydrochloride)
(+)-Niguldipine hydrochloride is an antagonist for calcium channel. (+)-Niguldipine hydrochloride produces vasodilation by blocking calcium channels and reducing the transmembrane influx of calcium ions. (+)-Niguldipine hydrochloride inhibits U-46619 (HY-108566)-induced coronary vasoconstriction in guinea pig Langendorff heart with pID50 of 11.37, binds to calcium channel on guinea pig skeletal muscle membrane with Ki of 9.75, and lowers the blood pressure in spontaneously hypertensive rat with pED30 of 7.1. (+)-Niguldipine hydrochloride ameliorates cardiovascular diseases such as hypertension, angina pectoris and arrhythmias[1].
Molecular Weight:
646.17
Purity:
98.06
CAS Number:
[113145-69-0]
Formula:
C36H40ClN3O6
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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