(-)-Niguldipine (hydrochloride), CAS [[113145-70-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-101390A
Supplier Catalog Number:
HY-101390A
Alternative Catalog Number:
MCE-HY-101390A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
(R)-Niguldipine (hydrochloride)
(-)-Niguldipine ((R)-Niguldipine) hydrochloride is a calcium channel antagonist. (-)-Niguldipine hydrochloride exerts a vasodilatory effect by blocking calcium channels and reducing the transmembrane influx of calcium ions. (-)-Niguldipine can inhibit U-46619 (HY-108566)-induced coronary artery contraction in guinea pig Langendorff hearts (pID50 of 9.93), has high affinity for calcium channel binding sites on guinea pig skeletal muscle membranes (Ki of 8.10), and lowers blood pressure in spontaneously hypertensive rats (pED30 of 5.55). (-)-Niguldipine hydrochloride can improve cardiovascular diseases such as hypertension, angina pectoris, and arrhythmias[1].
Molecular Weight:
646.17
CAS Number:
[113145-70-3]
Formula:
C36H40ClN3O6
Target:
Calcium Channel
Application Notes:
MCE Product type: Reference compound
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