(R)-Niguldipine, CAS [[120054-86-6]] Preis auf Anfrage

Product Overview

• Article Name: (R)-Niguldipine, CAS [[120054-86-6]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-101390D
• Supplier Catalog Number: HY-101390D
• Alternative Catalog Number: MCE-HY-101390D-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(R)-Niguldipine, a R-epimer of Niguldipine (HY-101390B), is a calcium channel antagonist. (R)-Niguldipine exerts a vasodilatory effect by blocking calcium channels and reducing the transmembrane influx of calcium ions. (R)-Niguldipine can inhibit U-46619 (HY-108566)-induced coronary artery contraction in guinea pig Langendorff hearts (pID50 of 9.93), has high affinity for calcium channel binding sites on guinea pig skeletal muscle membranes (Ki of 8.10), and lowers blood pressure in spontaneously hypertensive rats (pED30 of 5.55). (R)-Niguldipine can improve cardiovascular diseases such as hypertension, angina pectoris, and arrhythmias[1].

Product Properties

• Molecular Weight: 609.71
• CAS Number: [120054-86-6]
• Formula: C36H39N3O6
• Target: Calcium Channel

Application Notes

• Application Notes: MCE Product type: Reference compound