JNJ-47965567 is a centrally permeable, high-affinity, selective P2X7 antagonist, with pKis of 7.9 and 8.7 for human and rat P2X7, respectively. JNJ-47965567 can be used to probe the role of central P2X7 in rodent models of CNS pathophysiology[1].
Molecular Weight:
488.64
Purity:
99.79
CAS Number:
[1428327-31-4]
Formula:
C28H32N4O2S
Target:
P2X Receptor
Application Notes:
MCE Product type: Reference compound
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