HIOC is a potent and selective activator of TrkB (tropomyosin related kinase B) receptor. HIOC can pass the blood-brain and blood-retinal barriers.HIOC activates TrkB/ERK pathway and decreases neuronal cell apoptosis. HIOC attenuates early brain injury after SAH (subarachnoid hemorrhage). HIOC shows protective activity in an animal model for light-induced retinal degeneration[1][2][3].
Molecular Weight:
301.34
Purity:
99.94
CAS Number:
[314054-36-9]
Formula:
C16H19N3O3
Target:
Apoptosis,ERK,Trk Receptor
Application Notes:
MCE Product type: Reference compound
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