PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. PBIT inhibits JARID1B (KDM5B or PLU1) histone demethylase with an IC50 of about 3 µM . PBIT also inhibits JARID1A and JARID1C with IC50s of 6 µM and 4.9 µM, respectively[1].
Molecular Weight:
241.31
Purity:
99.46
CAS Number:
[2514-30-9]
Formula:
C14H11NOS
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound1
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