Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 µM (BRD4-1) and 62.55 µM (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1].
Molecular Weight:
571.58
Purity:
98.60
CAS Number:
[2087490-42-2]
Formula:
C29H29N7O6
Target:
Epigenetic Reader Domain,Molecular Glues,PROTACs
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
