Fenobam is a selective and orally active mGluR5 antagonist (IC50=84 nM) that can penetrate the blood-brain barrier. Fenobam shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction[1][2][3].
Molecular Weight:
266.69
Purity:
99.91
CAS Number:
[57653-26-6]
Formula:
C11H11ClN4O2
Target:
Apoptosis,mGluR
Application Notes:
MCE Product type: Reference compound
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