GZD856 formic is a potent and orally active PDGFRalpha/beta inhibitor, with IC50s of 68.6 and 136.6 nM, respectively. GZD856 formic is also a Bcr-AblT315I inhibitor, with IC50s of 19.9 and 15.4 nM for native Bcr-Abl and the T315I mutant. GZD856 formic has antitumor activity[1][2]. GZD856 (formic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
578.58
Purity:
95.36
CAS Number:
[2804039-78-7]
Formula:
C30H29F3N6O3
Target:
Apoptosis,Bcr-Abl,PDGFR
Application Notes:
MCE Product type: Reference compound
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