Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (-)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8[1].
Molecular Weight:
524.88
Purity:
99.47
CAS Number:
[1628287-16-0]
Formula:
C23H20ClF3N4O5
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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