eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 µM, Kd: 0.043 µM) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3].
Molecular Weight:
588.88
Purity:
99.96
CAS Number:
[2095486-67-0]
Formula:
C29H23BrClN5O2
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
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