Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner[2][3].
Molecular Weight:
642.59
Purity:
99.24
CAS Number:
[1818393-16-6]
Formula:
C34H38Cl2FN3O4
Target:
Apoptosis,E1/E2/E3 Enzyme,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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