TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 µM and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates Nomega-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence[1][2].
Molecular Weight:
428.82
Purity:
99.67
CAS Number:
[1190221-43-2]
Formula:
C21H17ClN2O6
Target:
Apoptosis,PAI-1
Application Notes:
MCE Product type: Reference compound
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