TyK2-IN-2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0.1 µM and 0.05 µM for TYK2 JH2, IL-23 and IFNalpha, respectively. TyK2-IN-2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2-IN-2 can be used for the research of inflammatory and autoimmune diseases[1].
Molecular Weight:
310.35
Purity:
99.71
CAS Number:
[2098466-94-3]
Formula:
C16H18N6O
Target:
JAK,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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