(S,R,S)-AHPC (dihydrochloride), CAS [[2137142-47-1]] Preis auf Anfrage

Product Overview

• Article Name: (S,R,S)-AHPC (dihydrochloride), CAS [[2137142-47-1]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-101763B
• Supplier Catalog Number: HY-101763B
• Alternative Catalog Number: MCE-HY-101763B-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: VH032-NH2 (dihydrochloride), VHL ligand 1 (dihydrochloride)

Product Description

(S,R,S)-AHPC (VH032-NH2) dihydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC dihydrochloride can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 µM in Ba/F3 cells[1].

Product Properties

• Molecular Weight: 503.49
• CAS Number: [2137142-47-1]
• Formula: C22H32Cl2N4O3S
• Target: Ligands for E3 Ligase

Application Notes

• Application Notes: MCE Product type: Reference compound