Emrusolmin (Anle138b), an oligomeric aggregation inhibitor, blocks the formation of pathological aggregates of prion protein (PrPSc) and of alpha-synuclein (alpha-syn). Emrusolmin strongly inhibits oligomer accumulation, neuronal degeneration, and disease progression in vivo. Emrusolmin has low toxicity and an excellent oral bioavailability and blood-brain-barrier penetration. Emrusolmin blocks Abeta channels and rescues disease phenotypes in a mouse model for amyloid pathology[1][2].
Molecular Weight:
343.17
Purity:
99.93
CAS Number:
[882697-00-9]
Formula:
C16H11BrN2O2
Target:
Amyloid-beta
Application Notes:
MCE Product type: Reference compound
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