CM-272 (Standard), CAS [[1846570-31-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-101925R
Supplier Catalog Number:
HY-101925R
Alternative Catalog Number:
MCE-HY-101925R-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
CM-272 (Standard) is the analytical standard of CM-272 (HY-101925). This product is intended for research and analytical applications. CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1].
