BEPP hydrochloride is a double-stranded RNA-dependent protein kinase (PKR) modulator. BEPP hydrochloride enhances the phosphorylation levels of PKR and eIF2alpha, activates caspase-3, upregulates the pro-apoptotic protein BAX, and downregulates the anti-apoptotic protein Bcl-2. BEPP hydrochloride inhibits vaccinia virus replication and exhibits selective cytotoxicity in cells expressing PKR. BEPP hydrochloride can be used in research related to cancer and viral infections[1].
Molecular Weight:
409.91
Purity:
99.62
CAS Number:
[455311-98-5]
Formula:
C23H24ClN3O2
Target:
Akt,Apoptosis,Bcl-2 Family,Caspase,Orthopoxvirus
Application Notes:
MCE Product type: Reference compound
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