BMS-1166 is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation[1][2].
Molecular Weight:
641.11
Purity:
99.64
CAS Number:
[1818314-88-3]
Formula:
C36H33ClN2O7
Target:
PD-1/PD-L1
Application Notes:
Reference compound
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