Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively[1].
Molecular Weight:
467.84
Purity:
99.57
CAS Number:
[1130115-44-4]
Formula:
C21H13D3ClF3N4O3
Target:
Apoptosis,Autophagy,Ferroptosis,FLT3,Raf,VEGFR
Application Notes:
Isotope-Labeled Compounds
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